60. Wolman RL, Nussmeier NA, Aggarwal A, et al:
Cerebral injury after cardiac surgery: Identifica-
tion of a group at extraordinary risk. Multicenter
Study of Perioperative Ischemia Research Group
(McSPI) and the Ischemia Research Education
Foundation (IREF) Investigators. Stroke 30:514–
522, 1999.
61. Bucerius J, Gummert JF, Borger MA, et al: Stroke
after cardiac surgery: A risk factor analysis of 16,184
consecutive adult patients. Ann Thorac Surg
75:472–478, 2003.
62. Newman MF, Kirchner JL, Phillips-Bute B, et al:
Longitudinal assessment of neurocognitive function
after coronary-artery bypass surgery. N Engl J Med
344:395–402, 2001.
63. Andrew MJ, Baker RA, Bennetts J, et al: A compa-
rison of neuropsychologic deficits after extracardiac
and intracaradiac surgery. J Cardiothorac Vasc
Anesth 15:9–14, 2001.
64. Neville MJ, Butterworth J, James RL, et al: Similar
neurobehavioral outcome after valve or coronary
artery operations despite differing carotid embolic
counts. J Thorac Cardiovasc Surg 121:125–136,
2001.
65. Währborg P, Booth JE, Clayton T, et al: Neuropsy-
chological outcome after percutaneous coronary
intervention or coronary artery bypass grafting:
Results from the Stent or Surgery (SoS) Trial. Cir-
culation 110:3411–3417, 2004.
66. Edmonds HL, Jr: Monitoring the nervous system
during cardiac and vascular surgery. Semin Cardio-
thorac Vasc Anesth 8:59–60, 2004.
67. Katz ES, Tunick PA, Rusinek H, et al: Protruding
aortic atheromas predict stroke in elderly patients
undergoing cardiopulmonary bypass: Experience
with intraoperative transesophageal echocardiogra-
phy. J Am Coll Cardiol 20:70–77, 1992.
68. Hartman GS, Yao FS, Bruefach M III, et al: Severity
of aortic atheromatous disease diagnosed by tran-
sesophageal echocardiography predicts stroke and
other outcomes associated with coronary artery
surgery: A prospective study. Anesth Analg 83:701–
708, 1996.
69. Davila-Roman VG, Barzilai B, Wareing TH, et al:
Atherosclerosis of the ascending aorta: Prevalence
and role as an independent predictor of cerebrovas-
cular events in cardiac patients. Stroke 25:2010–
2016, 1994.
70. Gold JP, Torres KE, Maldarelli W, et al: Improving
outcomes in coronary surgery: The impact of echo-
directed aortic cannulation and perioperative
hemodynamic management in 500 patients. Ann
Thorac Surg 78:1579–1585, 2004.
71. Wilson MJ, Boyd SY, Lisagor PG, et al: Ascending
aortic atheroma assessed intraoperatively by epiaor-
tic and transesophageal echocardiography. Ann
Thorac Surg 70:25–30, 2000.
72. Sylivris S, Calafiore P, Matalanis G, et al: The intrao-
perative assessment of ascending aortic atheroma:
Epiaortic imaging is superior to both transesopha-
geal echocardiography and direct palpation. J Car-
diothorac Vasc Anesth 11:704–707, 1997.
73. Pugsley W, Klinger L, Paschalis C, et al: The impact
of microemboli during cardiopulmonary bypass on
neuropsychological functioning. Stroke 25:1393–
1399, 1994.
74. Doblar DD: Intraoperative transcranial ultrasonic
monitoring for cardiac and vascular surgery. Semin
Cardiothorac Vasc Anesth 8:127–145, 2004.
75. Estrera AL, Garami Z, Miller CC III, et al: Cerebral
monitoring with transcranial Doppler ultrasono-
graphy improves neurologic outcome during repairs
of acute type A aortic dissection. J Thorac Cardio-
vasc Surg 129:277–285, 2005.
76. Sear JW: Kidney dysfunction in the postoperative
period. Br J Anaesth 95:20–32, 2005.
77. Gamoso MG, Phillips-Bute B, Landolfo KP, et al:
Off-pump versus on-pump coronary artery bypass
surgery and postoperative renal dysfunction.
Anesth Analg 91:1080–1084, 2000.
78. Baker RC, Armstrong MA, Allen SJ, et al: Role of the
kidney in perioperative inflammatory responses. Br
J Anaesth 88:330–334, 2002.
79. Gormley SM, McBride WT, Armstrong MA, et al:
Plasma and urinary cytokine homeostasis and renal
dysfunction during cardiac surgery. Anesthesiology
93:1210–1216, 2000.
80. Solomon R, Werner C, Mann D, et al: Effects of
saline, mannitol, and furosemide to prevent acute
decreases in renal function induced by radiocon-
trast agents. N Engl J Med 331:1416–1420, 1994.
81. Bove T, Calabro MG, Landoni G, et al: The inci-
dence and risk of acute renal failure after cardiac
surgery. J Cardiothorac Vasc Anesth 18:442–445,
2004.
82. Asimakopoulos G, Karagounis AP, Valencia O, et al:
Renal function after cardiac surgery off- versus
on-pump coronary artery bypass: Analysis using
the Cockroft-Gault formula for estimating creati-
nine clearance. Ann Thorac Surg 79:2024–2031,
2005.
83. Mangano CM, Diamondstone LS, Ramsay JG, et al:
Renal dysfunction after myocardial revasculariza-
tion: Risk factors, adverse outcomes, and hospital
resource utilization. The Multicenter Study of Perio-
perative Ischemia Research Group. Ann Intern Med
128:194–203, 1998.
84. Rassias AJ: Intraoperative management of hyper-
glycemia in the cardiac surgical patient. Semin
Thorac Cardiovasc Surg 18:330–338, 2006.
85. Wade AO, Cordingley JJ: Glycaemic control in cri-
tically ill patients with cardiovascular disease. Curr
Opin Crit Care 12:437–443, 2006.
86. Van den Berghe G: Does tight blood glucose control
during cardiac surgery improve patient outcome?
Ann Intern Med 146:307–308, 2007.
87. Gandhi GY, Nuttall GA, Abel MD, et al: Intensive
intraoperative insulin therapy versus conventional
glucose management during cardiac surgery: A
randomized trial. Ann Intern Med 146:233–243,
2007.
88. Streeter NB: Considerations in prevention of surgi-
cal site infections following cardiac surgery: When
your patient is diabetic. J Cardiovasc Nurs 21:E14–
E20, 2006.
89. Bennett-Guerrero E, Jimenez JL, White WD, et al:
Cardiovascular effects of intravenous triiodothyro-
nine in patients undergoing coronary artery bypass
graft surgery: A randomized, double-blind, placebo-
controlled trial. Duke T3 Study Group. JAMA
275:687–692, 1996.
90. Eagle KA, Guyton RA, Davidoff R, et al: ACC/AHA
2004 guideline update for coronary artery bypass
graft surgery: A report of the American College of
Cardiology/American Heart Association Task Force
on Practice Guidelines (Committee to Update the
1999 Guidelines for Coronary Artery Bypass Graft
Surgery). Circulation 110:e340–e437, 2004.
91. Zindrou D, Taylor KM, Bagger JP: Excess coronary
artery bypass graft mortality among women with
hypothyroidism. Ann Thorac Surg 74:2121–2125,
2002.
92. Christakis GT, Weisel RD, Buth KJ, et al: Is body size
the cause for poor outcomes of coronary artery
bypass operations in women? J Thorac Cardiovasc
Surg 110:1344–1356, 1995.
93. Grady D, Herrington D, Bittner V, et al: Cardiovas-
cular disease outcomes during 6.8 years of hormone
therapy: Heart and Estrogen/Progestin Replace-
ment Study follow-up (HERS II). JAMA 288:49–57,
2002.
94. Herrington DM, Reboussin DM, Brosnihan KB,
et al: Effects of estrogen replacement on the pro-
gression of coronary-artery atherosclerosis. N Engl
J Med 343:522–529, 2000.
95. Hulley S, Grady D, Bush T, et al: Randomized trial
of estrogen plus progestin for secondary prevention
of coronary heart disease in postmenopausal
women. Heart and Estrogen/Progestin Replace-
ment Study (HERS) Research Group. JAMA
280:605–613, 1998.
96. Nussmeier NA, MarinoMR, VaughnWK: Hormone
replacement therapy is associated with improved
survival in women undergoing coronary artery
bypass grafting. JThorac Cardiovasc Surg 124:1225–
1229, 2002.
97. Shackelford DP, Daniels S, Hoffman MK, et al:
Estrogen therapy in women undergoing coronary
artery bypass grafting: Effect on surgical complica-
tions. Obstet Gynecol 95:732–735, 2000.
98. Sullivan JM, El-Zeky F, Vander Zwaag R, et al: Effect
on survival of estrogen replacement therapy after
coronary artery bypass grafting. Am J Cardiol
79:847–850, 1997.
99. Nussmeier NA, Mora-Mangano C, Fontes M, et al:
Hormone replacement therapy is safe in women
undergoing coronary artery bypass grafting. Tex
Heart Inst J 32:507–514, 2005.
100. Hartmann M, Sucker C, Boehm O, et al: Effects of
cardiac surgery on hemostasis. Transfus Med Rev
20:230–241, 2006.
101. Shander A, Moskowitz D, Rijhwani TS: The safety
and efficacy of “bloodless” cardiac surgery. Semin
Cardiothorac Vasc Anesth 9:53–63, 2005.
102. Herbertson M: Recombinant activated factor VII in
cardiacsurgery.BloodCoagulFibrinolysis15(Suppl1)
S31–S32, 2004.
103. Michalopoulos A, Tzelepis G, Dafni U, et al: Deter-
minants of hospital mortality after coronary artery
bypass grafting. Chest 115:1598–1603, 1999.
104. Leal-Noval SR, Rincon-Ferrari MD, Garcia-Curiel
A, et al: Transfusion of blood components and
postoperative infection in patients undergoing
cardiac surgery. Chest 119:1461–1468, 2001.
105. Vamvakas EC, Carven JH: Allogeneic blood trans-
fusion and postoperative duration of mechanical
ventilation: Effects of red cell supernatant, platelet
supernatant, plasma components and total transfu-
sed fluid. Vox Sang 82:141–149, 2002.
106. Ranucci M, Pavesi M, Mazza E, et al: Risk factors for
renal dysfunction after coronary surgery: The role
of cardiopulmonary bypass technique. Perfusion
9:319–326, 1994.
107. Koch CG, Khandwala F, Li L, et al: Persistent effect
of red cell transfusion on health-related quality of
life after cardiac surgery. AnnThorac Surg 82:13–20,
2006.
108. Hirsh J, Warkentin TE, Shaughnessy SG, et al:
Heparin and low-molecular-weight hepar: Mecha-
nisms of action, pharmacokinetics, dosing, monito-
ring, efficacy safety. Chest 119:64S–94S, 2001.
109. Hirsh J, Anand SS, Halperin JL, et al: Guide to anti-
coagulant therapy: Heparin: A statement for health-
care professionals from the American Heart
Association. Circulation 103:2994–3018, 2001.
109a. Bull BS, HuseWM, Brauer FS, et al: Heparin therapy
during extracorporeal circulation. II. The use of a
dose-respone curve to individualize heparain and
protamine dosage. J Thorac Cardiovasc Surg
69:685–689, 1975.
110. Young JA, Kisker CT, Doty DB: Adequate anticoa-
gulation during cardiopulmonary bypass determi-
ned by activated clotting time and the appearance
of fibrin monomer. Ann Thorac Surg 26:231–240,
1978.
111. Doty DB, Knott HW, Hoyt JL, et al: Heparin dose
for accurate anticoagulation in cardiac surgery. J
Cardiovasc Surg (Torino) 20:597–604, 1979.
112. Shore-Lesserson L: Evidence based coagulation
monitors: Heparin monitoring, thromboelastogra-
phy, and platelet function. Semin Cardiothorac Vasc
Anesth 9:41–52, 2005.
113. Aggarwal A, Sobel BE, Schneider DJ: Decreased
platelet reactivity in blood anticoagulated with
bivalirudin or enoxaparin compared with unfrac-
tionated heparin: Implications for coronary inter-
vention. J Thromb Thrombolysis 13:161–165, 2002.
114. Despotis GJ, Summerfield AL, Joist JH, et al: Com-
parison of activated coagulation time and whole
blood heparin measurements with laboratory
plasma anti-Xa heparin concentration in patients
having cardiac operations. JThorac Cardiovasc Surg
108:1076–1082, 1994.
115. Shore-Lesserson L: Coagulation monitoring. In
Kaplan JA, Reich DL, Lake CL, et al (eds): Kaplan’s
Cardiac Anesthesia, 5th ed. Philadelphia, Elsevier
Saunders, 2006, pp 557–583.
116.
DespotisGJ,JoistJH,HogueCWJr
,etal:Moreeffec-
tive suppression of hemostatic system activation in
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