10. Liu S, Carpenter RL, Neal JM: Epidural anesthesia
and analgesia. Their role in postoperative outcome.
Anesthesiology 82:1474, 1995.
11. Kehlet H: Modification of responses to surgery by
neural blockade.
In
Cousins MJ, Bridenbaugh PO
(eds): Neural Blockade in Clinical Anesthesia and
Management of Pain, 3rd ed. Philadelphia, Lippin-
cott-Raven, 1998.
12. Desborough JP: The stress response to trauma and
surgery. Br J Anaesth 85:109, 2000.
13. Wu CL, Fleisher LA: Outcomes research in regional
anesthesia and analgesia. Anesth Analg 91:1232,
2000.
14. Kehlet H, Jensen TS, Woolf CJ: Persistent postsur-
gical pain: Risk factors and prevention. Lancet
3367:1618, 2006.
15. Macrae WA: Chronic pain after surgery. Br J
Anaesth 87:88, 2001.
16. Eisenach JC: Treating and preventing chronic pain:
A view from the spinal cord—Bonica Lecture,
ASRA Annual Meeting, 2005. Reg Anesth Pain Med
31:146, 2006.
17. Capdevila X, Barthelet Y, Biboulet P, et al: Effects of
perioperative analgesic technique on the surgical
outcome and duration of rehabilitation after major
knee surgery. Anesthesiology 91:8, 1999.
18. Carli F, Mayo N, Klubien K, et al: Epidural analge-
sia enhances functional exercise capacity and
health-related quality of life after colonic surgery:
Results of a randomized trial. Anesthesiology
97:540, 2002.
19. Moiniche S, Kehlet H, Dahl JB: A qualitative and
quantitative systematic review of preemptive anal-
gesia for postoperative pain: The role of timing of
analgesia. Anesthesiology 96:725, 2002.
20. Ong CK, Lirk P, Seymour RA, Jenkins BJ: The effi-
cacy of preemptive analgesia for acute postoperative
pain management: A meta-analysis. Anesth Analg
100:757, 2005.
21. Kehlet H: Multimodal approach to control postope-
rative pathophysiology and rehabilitation. Br J
Anaesth 78:606, 1997.
22. Boisseau N, Rabary O, Padovani B, et al: Improve-
ment of “dynamic analgesia” does not decrease
atelectasis after thoracotomy. Br J Anaesth 87:564,
2001.
23. Kehlet H, Wilmore DW: Multimodal strategies to
improve surgical outcome. Am J Surg 183:630,
2002.
24. Stein C: The control of pain in peripheral tissue by
opioids. N Engl J Med 332:1685, 1995.
25. Gourlay GK, Kowalski SR, Plummer JL, et al: Fen-
tanyl blood concentration–analgesic response rela-
tionship in the treatment of postoperative pain.
Anesth Analg 67:329, 1988.
26. Ginsberg B, Sinatra RS, Adler LJ, et al: Conversion
to oral controlled-release oxycodone from intrave-
nous opioid analgesic in the postoperative setting.
Pain Med 4:31-38, 2003.
27. Viscusi ER, Reynolds L, Chung F, et al: Patient-con-
trolled transdermal fentanyl hydrochloride vs intra-
venous morphine pump for postoperative pain: A
randomized controlled trial. JAMA 291:1333,
2004.
28. Macintyre PE: Safety and efficacy of patient-
controlled analgesia. Br J Anaesth 87:36, 2001.
29. Camu F, Van Aken H, Bovill JG: Postoperative
analgesic effects of three demand-dose sizes of
fentanyl administered by patient-controlled analge-
sia. Anesth Analg 87:890, 1998.
30. Dawson PJ, Libreri FC, Jones DJ, et al: The efficacy
of adding a continuous intravenous morphine
infusion to patient-controlled analgesia (PCA) in
abdominal surgery. Anaesth Intensive Care 23:453,
1995.
31. Looi-Lyons LC, Chung FF, Chan VW, et al: Respira-
tory depression: An adverse outcome during
patient-controlled analgesia therapy. J Clin Anesth
8:151, 1996.
32. Parker RK, Holtmann B, White PF: Effects of a
nighttime opioid infusion with PCA therapy on
patient comfort and analgesic requirements after
abdominal hysterectomy. Anesthesiology 76:362,
1992.
33. Hudcova J, McNicol E, Quah C, et al: Patient con-
trolled opioid analgesia versus conventional opioid
analgesia for postoperative pain. Cochrane Data-
base Syst Rev 4:CD003348, 2006.
34. Chan VW, Chung F, McQuestion M, et al: Impact of
patient-controlled analgesia on required nursing
time and duration of postoperative recovery. Reg
Anesth 20:506, 1995.
35. Thomas V, Heath M, Rose D, et al: Psychological
characteristics and the effectiveness of patient-con-
trolled analgesia. Br J Anaesth 74:271, 1995.
36. Pellino TA, Ward SE: Perceived control mediates
the relationship between pain severity and patient
satisfaction. J Pain Symptom Manage 15:110,
1998.
37. Badner NH, Komar WE, Craen RA: Patient attitu-
des regarding PCA and associated costs. Can J
Anaesth 44:255, 1997.
38. Wu CL, Naqibuddin M, Fleisher LA: Measurement
of patient satisfaction as an outcome of regional
anesthesia and analgesia. Reg Anesth Pain Med
26:196, 2001.
39. Etches RC: Respiratory depression associated with
patient-controlled analgesia: A review of eight
cases. Can J Anaesth 41:125, 1994.
40. Svensson CI, Yaksh TL: The spinal phospholipase-
cyclooxygenase-prostanoid cascade in nociceptive
processing. Annu Rev Pharmacol Toxicol 42:553,
2002.
41. Sinatra R: Role of COX-2 inhibitors in the evolution
of acute pain management. J Pain SymptomManage
24(Suppl):S18, 2002.
42. Kis B, Snipes JA, Busija DW: Acetaminophen and
the cyclooxygenase-3 puzzle: Sorting out facts, fic-
tions, and uncertainties. J Pharmacol Exp Ther
315:1, 2005.
43. Sia AT, Chong JL: Epidural 0.2% ropivacaine for
labour analgesia: Parturient-controlled or conti-
nuous infusion? Anaesth Intensive Care 27:154,
1999.
44. Elia N, Lysakowski C, Tramer MR: Does multimo-
dal analgesia with acetaminophen, nonsteroidal
antiinflammatory drugs, or selective cyclooxyge-
nase-2 inhibitors and patient-controlled analgesia
morphine offer advantages over morphine alone?
Meta-analyses of randomized trials. Anesthesiology
103:1296, 2005.
45. Remy C, Marret E, Bonnet F: Effects of acetamino-
phen on morphine side-effects and consumption
after major surgery: Meta-analysis of randomized
controlled trials. Br J Anaesth 94:505, 2005.
46. Straube S, Derry S, McQuay HJ, Moore RA: Effect
of preoperative Cox-II–selective NSAIDs (coxibs)
on postoperative outcomes: A systematic review of
randomized studies. Acta Anaesthesiol Scand
49:601, 2005.
47. Marret E, Kurdi O, Zufferey P, Bonnet F: Effects of
nonsteroidal antiinflammatory drugs on patient-con-
trolled analgesia morphine side effects: Meta-analysis
of randomized controlled trials. Anesthesiology
102:1249, 2005.
48. Fitzgerald GA: Cardiovascular pharmacology of
nonselective nonsteroidal anti-inflammatory drugs
and coxibs: Clinical considerations. Am J Cardiol
89:26D, 2002.
49. Strom BL, Berlin JA, Kinman JL, et al: Parenteral
ketorolac and risk of gastrointestinal and operative
site bleeding. A postmarketing surveillance study.
JAMA 275:376, 1996.
50. Whelton A: Nephrotoxicity of nonsteroidal antiin-
flammatory drugs: Physiologic foundations and
clinical implications. Am J Med 106:13S, 1999.
51. Lee A, Cooper MG, Craig JC, et al: The effects of
non steroidal anti-inflammatory drugs (NSAIDs)
on postoperative renal function: A meta-analysis.
Anaesth Intensive Care 27:574, 1999.
52. Settipane RA, Schrank PJ, Simon RA, et al: Preva-
lence of cross-sensitivity with acetaminophen in
aspirin-sensitive asthmatic subjects. J Allergy Clin
Immunol 96:480, 1995.
53. Laine L: Gastrointestinal safety of coxibs and outco-
mes studies: What’s the verdict? J Pain Symptom
Manage 23(Suppl 2):S5, 2002.
54. Leese PT, Hubbard RC, Karim A, et al: Effects of
celecoxib, a novel cyclooxygenase-2 inhibitor, on
platelet function in healthy adults: A randomized,
controlled trial. J Clin Pharmacol 40:124, 2000.
55. Brophy JM: Celecoxib and cardiovascular risks.
Expert Opin Drug Saf 4:1005, 2005.
56. Kharasch ED: Perioperative COX-2 inhibitors:
Knowledge and challenges. Anesth Analg 98:1,
2004.
57. Nussmeier NA, Whelton AA, Brown MT, et al:
Complications of the COX-2 inhibitors parecoxib
and valdecoxib after cardiac surgery. N Engl J Med
352:1081-1091, 2005.
58. Celerier E, Rivat C, Jun Y, et al: Long-lasting hype-
ralgesia induced by fentanyl in rats: Preventive
effect of ketamine. Anesthesiology 92:465, 2000.
59. Bell RF, Dahl JB, Moore RA, Kalso E: Perioperative
ketamine for acute postoperative pain. Cochrane
Database Syst Rev 1:CD004603, 2006.
60. Sethna NF, Liu M, Gracely R, et al: Analgesic and
cognitive effects of intravenous ketamine-alfentanil
combinations versus either drug alone after intra-
dermal capsaicin in normal subjects. Anesth Analg
86:1250, 1998.
61. Wong CS, LiawWJ, Tung CS, et al: Ketamine poten-
tiates analgesic effect of morphine in postoperative
epidural pain control. Reg Anesth 21:534, 1996.
62. Hawksworth C, Serpell M: Intrathecal anesthesia
with ketamine. Reg Anesth Pain Med 23:283,
1998.
63. Pang WW, Huang PY, Chang DP, et al: The periphe-
ral analgesic effect of tramadol in reducing propofol
injection: A comparison with lidocaine. Reg Anesth
Pain Med 24:246, 1999.
64. Edwards JE, McQuay HJ, Moore RA: Combination
analgesic efficacy: Individual patient data meta-
analysis of single-dose oral tramadol plus acetami-
nophen in acute postoperative pain. J Pain Symptom
Manage 23:121, 2002.
65. Budd K, Langford R: Tramadol revisited. Br J
Anaesth 82:493, 1999.
66. Dolin SJ, Cashman JN, Bland JM: Effectiveness of
acute postoperative pain management: I. Evidence
from published data. Br J Anaesth 89:409, 2002.
67. Hamber EA, Viscomi CM: Intrathecal lipophilic
opioids as adjuncts to surgical spinal anesthesia.
Reg Anesth Pain Med 24:255, 1999.
68. Liu SS, Bernards CM: Exploring the epidural trial.
Reg Anesth Pain Med 27:122, 2002.
69. Liu SS, MacDonald SB: Current issues in spinal
anesthesia. Anesthesiology 94:888, 2001.
70. Birnbach DJ, Johnson MD, Arcario T, et al: Effect of
diluent volume on analgesia produced by epidural
fentanyl. Anesth Analg 68:808, 1989.
71. Beattie WS, Buckley DN, Forrest JB: Epidural mor-
phine reduces the risk of postoperative myocardial
ischaemia in patients with cardiac risk factors. Can
J Anaesth 40:532, 1993.
72. Tsui SL, Law S, Fok M, et al: Postoperative analgesia
reduces mortality and morbidity after esophagec-
tomy. Am J Surg 173:472, 1997.
73. Viscusi ER, Martin G, Hartrick CT, et al: Forty-eight
hours of postoperative pain relief after total hip
arthroplasty with a novel, extended-release epidural
morphine formulation. Anesthesiology 102:1014,
2005.
74. Wheatley RG, Schug SA, Watson D: Safety and
efficacy of postoperative epidural analgesia. Br J
Anaesth 87:47, 2001.
75. Wu CL, Cohen SR, Richman JM, et al: Efficacy of
postoperative patient-controlled and continuous
infusion epidural analgesia versus intravenous
patient-controlled analgesia with opioids: A meta-
analysis. Anesthesiology 103:1079, 2005.
76. Block BM, Liu SS, Rowlingson AJ, et al: Efficacy of
postoperative epidural analgesia: A meta-analysis.
JAMA 290:2455, 2003.
77. Handley GH, Silbert BS, Mooney PH, et al: Combi-
ned general and epidural anesthesia versus general
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