139. Newman J, Baars BJ: A neural attentional model of
access to consciousness: A global workspace pers-
pective. Concepts Neurosci 4:255, 1993.
140. Bogen JE: On the neurophysiology of conscious-
ness, parts I and II. Conscious Cogn 4:52, 1995.
141. Edelman GM: The Remembered Present: A Biolo-
gical Theory of Consciousness. New York, Basic
Books, 1989.
142. Logothetis NK, Schall JD: Neuronal correlates of
subjective visual perception. Science 245:761,
1989.
143. Tootell RB, Reppas JB, Dale AM, et al:Visual motion
aftereffect in human cortical area MT revealed by
functional magnetic resonance imaging. Nature
375:139, 1995.
144. Crick F, Koch C: Are we aware of neural activity in
primary visual cortex? Nature 375:121, 1995.
145. Cotterill R: On the unity of conscious experience. J
Consciousness Stud 2:290, 1994.
146. Cauller LJ, Kulics AT: The neural basis of the beha-
viorally relevant N1 component of the somatosen-
sory-evoked potential in SI cortex of awake
monkeys: Evidence that backward cortical projec-
tions signal conscious touch sensation. Exp Brain
Res 84:607, 1991.
147. Rees G, Kreiman G, Koch C: Neural correlates
of consciousness in humans. Nat Rev Neurosci
3:261, 2002.
148. Velly LJ, Rey MF, Bruder NJ, et al: Differential
dynamic of action on cortical and subcortical struc-
tures of anesthetic agents during induction of anes-
thesia. Anesthesiology 107:202, 2007.
149. White NS, Alkire MT: Impaired thalamocortical
connectivity in humans during general-anesthetic–
induced unconsciousness. Neuroimage 19:402,
2003.
150. Friston KJ, Buechel C, Fink GR, et al: Psychophysio-
logical and modulatory interactions in neuroima-
ging. Neuroimage 6:218, 1997.
151. Ying SW, Abbas SY, Harrison NL, et al: Propofol
block of I(h) contributes to the suppression of neu-
ronal excitability and rhythmic burst firing in tha-
lamocortical neurons. Eur J Neurosci 23:465,
2006.
152. John ER, Prichep LS, Kox W, et al: Invariant rever-
sible QEEG effects of anesthetics. Conscious Cogn
10:165, 2001.
153. Imas OA, Ropella KM,Ward BD, et al: Volatile anes-
thetics disrupt frontal-posterior recurrent informa-
tion transfer at gamma frequencies in rat. Neurosci
Lett 387:145, 2005.
154. Peltier SJ, Kerssens C, Hamann SB, et al: Functional
connectivity changes with concentration of sevoflu-
rane anesthesia. Neuroreport 16:285, 2005.
155. Mashour GA: Consciousness unbound: Toward a
paradigm of general anesthesia. Anesthesiology
100:428, 2004.
156. Mashour GA: Integrating the science of conscious-
ness and anesthesia. Anesth Analg 103:975, 2006.
157. Pack CC, Berezovskii VK, Born RT: Dynamic pro-
perties of neurons in cortical area MT in alert and
anaesthetized macaque monkeys. Nature 414:905,
2001.
158. John ER, Prichep LS: The anesthetic cascade: A
theory of how anesthesia suppresses consciousness.
Anesthesiology 102:447, 2005.
159. Sakai T, Singh H, Mi WD, et al: The effect of keta-
mine on clinical endpoints of hypnosis and EEG
variables during propofol infusion. Acta Anaesthe-
siol Scand 43:212, 1999.
160. Yamamura T, Fukuda M, Takeya H, et al: Fast osci-
llatory EEG activity induced by analgesic concentra-
tions of nitrous oxide in man. Anesth Analg 60:283,
1981.
161. Walling PT, Hicks KN: Nonlinear changes in brain
dynamics during emergence from sevoflurane anes-
thesia: Preliminary exploration using new software.
Anesthesiology 105:927, 2006.
162. Schiff ND, Ribary U, Moreno DR, et al: Residual
cerebral activity and behavioural fragments can
remain in the persistently vegetative brain. Brain
125:1210, 2002.
163. Laureys S, Goldman S, Phillips C, et al: Impaired
effective cortical connectivity in vegetative state: Pre-
liminary investigation using PET. Neuroimage 9:377,
1999.
164. Laureys S: The neural correlate of (un)awareness:
Lessons from the vegetative state. Trends Cogn Sci
9:556, 2005.
165. Laureys S, Faymonville ME, Luxen A, et al: Restora-
tion of thalamocortical connectivity after recovery
from persistent vegetative state. Lancet 355:1790,
2000.
166. Lydic R, Baghdoyan HA: Sleep, anesthesiology, and
the neurobiology of arousal state control. Anesthe-
siology 103:1268, 2005.
167. Massimini M,Ferrarelli F,Huber R,et al: Breakdown
of cortical effective connectivity during sleep.
Science 309:2228, 2005.
168. Leslie K, Skrzypek H, Paech MJ, et al: Dreaming
during anesthesia and anesthetic depth in elective
surgery patients: A prospective cohort study. Anes-
thesiology 106:33, 2007.
169. Sebel PS, Bowdle TA, Ghoneim MM, et al: The
incidence of awareness during anesthesia: A
multicenter United States study. Anesth Analg
99:833, 2004.
170. Sandin RH, Enlund G, Samuelsson P, et al: Aware-
ness during anaesthesia: A prospective case study.
Lancet 355:707, 2000.
171. Pollard RJ, Coyle JP, Gilbert RL, et al: Intraoperative
awareness in a regional medical system: A review of
3 years’ data. Anesthesiology 106:269, 2007.
172. Osterman JE, van der Kolk BA: Awareness during
anesthesia and posttraumatic stress disorder. Gen
Hosp Psychiatry 20:274, 1998.
173. Samuelsson P, Brudin L, Sandin RH: Late psycholo-
gical symptoms after awareness among consecuti-
vely included surgical patients. Anesthesiology
106:26, 2007.
174. Gibbs FA, Gibbs LE, LennoxWG: Effect on the elec-
troencephalogram of certain drugs which influence
nervous activity. Arch Intern Med 60:154, 1937.
175. Rampil IJ: A primer for EEG signal processing in
anesthesia. Anesthesiology 89:980, 1998.
176. Rosow C, Manberg PJ: Bispectral index monitoring.
Anesthesiol Clin North Am 19:947, 2001.
177. Kreuer S, Bruhn J, Larsen R, et al: Application of
Bispectral Index and Narcotrend index to the mea-
surement of the electroencephalographic effects of
isoflurane with and without burst suppression.
Anesthesiology 101:847, 2004.
178. Dressler O, Schneider G, Stockmanns G, et al:
Awareness and the EEG power spectrum: Analysis
of frequencies. Br J Anaesth 93:806, 2004.
179. Shannon CE: A mathematical theory of communi-
cation. Bell System Technical J 27:379, 623, 1948.
180. Vakkuri A, Yli-Hankala A, Talja P, et al: Time-
frequency balanced spectral entropy as a measure
of anesthetic drug effect in central nervous
system during sevoflurane, propofol, and thio-
pental anesthesia.Acta Anaesthesiol Scand 48:145,
2004.
181. Scheller B, Schneider G, Daunderer M, et al: High-
frequency components of auditory evoked poten-
tials are detected in responsive but not in
unconscious patients. Anesthesiology 103:944,
2005.
182. Schneider G, Hollweck R, Ningler M, et al: Detec-
tion of consciousness by electroencephalogram
and auditory evoked potentials. Anesthesiology
103:934, 2005.
183. Sebel PS, Lang E, Rampil IJ, et al: A multicenter
study of bispectral electroencephalogram analysis
for monitoring anesthetic effect. Anesth Analg
84:891, 1997.
184. Flaishon R, Windsor A, Sigl J, et al: Recovery of
consciousness after thiopental or propofol. Bispec-
tral index and isolated forearm technique. Anesthe-
siology 86:613, 1997.
185. Glass PS, Bloom M, Kearse L, et al: Bispectral analy-
sis measures sedation and memory effects of propo-
fol, midazolam, isoflurane, and alfentanil in healthy
volunteers. Anesthesiology 86:836, 1997.
186. Katoh T, Bito H, Sato S: Influence of age on hyp-
notic requirement, bispectral index, and 95%
spectral edge frequency associated with sedation
induced by sevoflurane. Anesthesiology 92:55,
2000.
187. Kearse LA Jr, Rosow C, Zaslavsky A, et al: Bis-
pectral analysis of the electroencephalogram
predicts conscious processing of information
during propofol sedation and hypnosis. Anes-
thesiology 88:25, 1998.
188. Denman WT, Swanson EL, Rosow D, et al: Pedia-
tric evaluation of the bispectral index (BIS)
monitor and correlation of BIS with end-tidal
sevoflurane concentration in infants and children.
Anesth Analg 90:872, 2000.
189. Whyte SD, Booker PD: Bispectral index during iso-
flurane anesthesia in pediatric patients. Anesth
Analg 98:1644, 2004.
190. Myles PS, Leslie K, McNeil J, et al: Bispectral index
monitoring to prevent awareness during anaesthe-
sia: The B-Aware randomised controlled trial.
Lancet 363:1757, 2004.
191. Chen X, Tang J, White PF, et al: A comparison of
patient state index and bispectral index values
during the perioperative period. Anesth Analg
95:1669, 2002.
192. White PF, Tang J, Ma H, et al: Is the patient state
analyzer with the PSArray2 a cost-effective alter-
native to the bispectral index monitor during the
perioperative period? Anesth Analg 99:1429,
2004.
193. Schmidt GN, Bischoff P, Standl T, et al: Compa-
rative evaluation of Narcotrend, Bispectral Index,
and classical electroencephalographic variables
during induction, maintenance, and emergence
of a propofol/remifentanil anesthesia. Anesth
Analg 98:1346, 2004.
194. Ellerkmann RK, Liermann VM, Alves TM, et al:
Spectral entropy and bispectral index as measures
of the electroencephalographic effects of sevoflu-
rane. Anesthesiology 101:1275, 2004.
195. Schmidt GN, Bischoff P, Standl T, et al: Compara-
tive evaluation of the Datex-Ohmeda S/5 Entropy
Module and the Bispectral Index monitor during
propofol-remifentanil anesthesia. Anesthesiology
101:1283, 2004.
196. Iannuzzi M, Iannuzzi E, Rossi F, et al: Relation-
ship between Bispectral Index, electroencepha-
lographic state entropy and effect-site EC
50
for
propofol at different clinical endpoints. Br J
Anaesth 94:492, 2005.
197. White PF, Tang J, Romero GF, et al: A comparison
of state and response entropy versus bispectral
index values during the perioperative period.Anesth
Analg 102:160, 2006.
198. Dahaba AA: Different conditions that could result
in the bispectral index indicating an incorrect hyp-
notic state. Anesth Analg 101:765, 2005.
199. Rampil IJ, Kim JS, Lenhardt R, et al: Bispectral EEG
index during nitrous oxide administration. Anes-
thesiology 89:671, 1998.
200. Vereecke HE, Struys MM, Mortier EP: A compari-
son of bispectral index and ARX-derived auditory
evoked potential index in measuring the clinical
interaction between ketamine and propofol anaes-
thesia. Anaesthesia 58:957, 2003.
201. Hering W, Geisslinger G, Kamp HD, et al: Changes
in the EEG power spectrum after midazolam anaes-
thesia combined with racemic or
S
- (+) ketamine.
Acta Anaesthesiol Scand 38:719, 1994.
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