Miller Anestesia

Óxido nítrico y vasodilatadores pulmonares inhalatorios

719

Sección II

Farmacología y anestesia

nitric oxide synthase–deficient mouse.Am J Physiol

Lung Cell Mol Physiol 284:L964-L971, 2003.

32. Balasubramaniam V, Maxey AM, Morgan DB, et al:

Inhaled NO restores lung structure in eNOS-deficient

mice recovering from neonatal hypoxia.Am J Physiol

Lung Cell Mol Physiol 291:L119-L127, 2006.

33. Roberts JD Jr, Roberts CT, Jones RC, et al: Conti-

nuous nitric oxide inhalation reduces pulmonary

arterial structural changes, right ventricular hyper-

trophy, and growth retardation in the hypoxic

newborn rat. Circ Res 76:215-222, 1995.

34. Kinsella JP, McQueston JA, Rosenberg AA, Abman

SH: Hemodynamic effects of exogenous nitric oxide

in ovine transitional pulmonary circulation. Am J

Physiol 263:H875-H880, 1992.

35. Roberts JD Jr, Chen TY, Kawai N, et al: Inhaled

nitric oxide reverses pulmonary vasoconstriction in

the hypoxic and acidotic newborn lamb. Circ Res

72:246-254, 1993.

36. Zayek M, Wild L, Roberts JD, Morin FC III: Effect

of nitric oxide on the survival rate and incidence of

lung injury in newborn lambs with persistent pul-

monary hypertension. J Pediatr 123:947-952, 1993.

37. Wilcox DT, Glick PL, Karamanoukian HL, et al:

Partial liquid ventilation and nitric oxide in congeni-

tal diaphragmatic hernia. J Pediatr Surg 32:1211-

1215, 1997.

38. Bourbon J, Boucherat O, Chailley-Heu B, Delacourt

C: Control mechanisms of lung alveolar develop-

ment and their disorders in bronchopulmonary

dysplasia. Pediatr Res 57:38R-46R, 2005.

39. McCurnin DC, Pierce RA, Chang LY, et al: Inhaled

NO improves early pulmonary function and modi-

fies lung growth and elastin deposition in a baboon

model of neonatal chronic lung disease.Am J Physiol

Lung Cell Mol Physiol 288:L450-L459, 2005.

40. Bland RD, Albertine KH, Carlton DP, MacRitchie

AJ: Inhaled nitric oxide effects on lung structure

and function in chronically ventilated preterm

lambs. Am J Respir Crit Care Med 172:899-906,

2005.

41. Lin YJ, Markham NE, Balasubramaniam V, et al:

Inhaled nitric oxide enhances distal lung growth

after exposure to hyperoxia in neonatal rats. Pediatr

Res 58:22-29, 2005.

42. Galambos C, Ng YS, Ali A, et al: Defective pulmo-

nary development in the absence of heparin-bin-

ding vascular endothelial growth factor isoforms.

Am J Respir Cell Mol Biol 27:194-203, 2002.

43. Tang JR, Markham NE, Lin YJ, et al: Inhaled nitric

oxide attenuates pulmonary hypertension and impro-

ves lung growth in infant rats after neonatal treatment

with a VEGF receptor inhibitor. Am J Physiol Lung

Cell Mol Physiol 287:L344-L351, 2004.

44. Inhaled nitric oxide and hypoxic respiratory failure

in infants with congenital diaphragmatic hernia.

The Neonatal Inhaled Nitric Oxide Study Group

(NINOS). Pediatrics 99:838-845, 1997.

45. Davidson D,Barefield ES,Kattwinkel J,et al: Inhaled

nitric oxide for the early treatment of persistent

pulmonary hypertension of the term newborn: A

randomized, double-masked, placebo-controlled,

dose-response, multicenter study. The I-NO/PPHN

Study Group. Pediatrics 101:325-334, 1998.

46. Kinsella JP, Greenough A, Abman SH: Bronchopul-

monary dysplasia. Lancet 367:1421-1431, 2006.

47. Kinsella JP,Walsh WF, Bose CL, et al: Inhaled nitric

oxide in premature neonates with severe hypoxae-

mic respiratory failure: A randomised controlled

trial. Lancet 354:1061-1065, 1999.

48. Schreiber MD, Gin-Mestan K, Marks JD, et al:

Inhaled nitric oxide in premature infants with the

respiratory distress syndrome. N Engl J Med

349:2099-2107, 2003.

49. Van Meurs KP, Wright LL, Ehrenkranz RA, et al:

Inhaled nitric oxide for premature infants with severe

respiratory failure. N Engl J Med 353:13-22, 2005.

50. Kinsella JP, Cutter GR, Walsh WF, et al: Early

inhaled nitric oxide therapy in premature newborns

with respiratory failure. N Engl J Med 355:354-364,

2006.

51. Ballard RA,TruogWE,CnaanA,et al: Inhaled nitric

oxide in preterm infants undergoing mechanical

ventilation. N Engl J Med 355:343-353, 2006.

52. Kinsella JP: Inhaled nitric oxide therapy in prema-

ture newborns. Curr Opin Pediatr 18:107-111,

2006.

53. Schwarz UR, Walter U, Eigenthaler M: Taming pla-

telets with cyclic nucleotides. Biochem Pharmacol

62:1153-1161, 2001.

54. Hogman M, Frostell C,Arnberg H, Hedenstierna G:

Bleeding time prolongation and NO inhalation.

Lancet 341:1664-1665, 1993.

55. Field D, Elbourne D, Truesdale A, et al: Neonatal

ventilation with inhaled nitric oxide versus ventila-

tory support without inhaled nitric oxide for preterm

infants with severe respiratory

failure:The

INNOVO

Multicentre Randomised Controlled Trial (ISRCTN

17821339). Pediatrics 115:926-936, 2005.

56. Mestan KKL, Marks JD, Hecox K, et al: Neurodeve-

lopmental outcomes of premature infants treated

with inhaled nitric oxide. N Engl J Med 353:23-32,

2005.

57. Rich S, Kaufmann E, Levy PS: The effect of high

doses of calcium-channel blockers on survival in

primary pulmonary hypertension. N Engl J Med

327:76-81, 1992.

58. Semigran MJ, Cockrill BA, Kacmarek R, et al:

Hemodynamic effects of inhaled nitric oxide in

heart failure. J Am Coll Cardiol 24:982-988, 1994.

59. Atz AM, Adatia I, Lock JE, Wessel DL: Combined

effects of nitric oxide and oxygen during acute pul-

monary vasodilator testing. J Am Coll Cardiol

33:813-819, 1999.

60. Krasuski RA,Warner JJ,Wang A,et al: Inhaled nitric

oxide selectively dilates pulmonary vasculature in

adult patients with pulmonary hypertension, irres-

pective of etiology. J Am Coll Cardiol 36:2204-2211,

2000.

61. Cockrill BA, Kacmarek RM, Fifer MA, et al: Com-

parison of the effects of nitric oxide, nitroprusside,

and nifedipine on hemodynamics and right ventri-

cular contractility in patients with chronic pulmo-

nary hypertension. Chest 119:128-136, 2001.

62. Sitbon O, Humbert M, Jagot JL, et al: Inhaled nitric

oxide as a screening agent for safely identifying res-

ponders to oral calcium-channel blockers in

primary pulmonary hypertension. Eur Respir J

12:265-270, 1998.

63. Ricciardi MJ, Knight BP, Martinez FJ, Rubenfire M:

Inhaled nitric oxide in primary pulmonary hyper-

tension: A safe and effective agent for predicting

response to nifedipine. J Am Coll Cardiol 32:1068-

1073, 1998.

64. Balzer DT, Kort HW, Day RW, et al: Inhaled nitric

oxide as a preoperative test (INOP test I): the INOP

Test Study Group. Circulation 106:I76-I81, 2002.

65. Robbins IM, Christman BW, Newman JH, et al: A

survey of diagnostic practices and the use of epo-

prostenol in patients with primary pulmonary

hypertension. Chest 114:1269-1275, 1998.

66. Waldman JD: From PediHeart: Inhaled nitric

oxide—in clinical trial or in clinical practice?

Pediatr Cardiol 21:274, 2000.

67. Barst RJ, Rubin LJ, McGoon MD, et al: Survival in

primary pulmonary hypertension with long-term

continuous intravenous prostacyclin. Ann Intern

Med 121:409-415, 1994.

68. Channick RN, Newhart JW, Johnson FW, et al:

Pulsed delivery of inhaled nitric oxide to patients

with primary pulmonary hypertension: An ambu-

latory delivery system and initial clinical tests.

Chest 109:1545-1549, 1996.

69. Perez-Penate G, Julia-Serda G, Pulido-Duque JM, et

al: One-year continuous inhaled nitric oxide for

primary pulmonary hypertension. Chest 119:970-

973, 2001.

70. Rubin LJ, Badesch DB, Barst RJ, et al: Bosentan

therapy for pulmonary arterial hypertension. N

Engl J Med 346:896-903, 2002.

71. Barst RJ, McGoon M, McLaughlin V, et al: Beraprost

therapy for pulmonary arterial hypertension. J Am

Coll Cardiol 41:2119-2125, 2003.

72. Ghofrani HA,Wiedemann R, Rose F, et al: Sildenafil

for treatment of lung fibrosis and pulmonary hyper-

tension: A randomised controlled trial. Lancet

360:895-900, 2002.

73. Inglessis I, Shin JT, Lepore JJ, et al: Hemodynamic

effects of inhaled nitric oxide in right ventricular

myocardial infarction and cardiogenic shock. J Am

Coll Cardiol 44:793-798, 2004.

74. Benzing A, Geiger K: Inhaled nitric oxide lowers

pulmonary capillary pressure and changes longitu-

dinal distribution of pulmonary vascular resistance

in patients with acute lung injury.Acta Anaesthesiol

Scand 38:640-645, 1994.

75. Benzing A, Brautigam P, Geiger K, et al: Inhaled

nitric oxide reduces pulmonary transvascular

albumin flux in patients with acute lung injury.

Anesthesiology 83:1153-1161, 1995.

76. Troncy E, Collet JP, Shapiro S, et al: Inhaled nitric

oxide in acute respiratory distress syndrome:A pilot

randomized controlled study.Am J Respir Crit Care

Med 157:1483-1488, 1998.

77. Dellinger RP, Zimmerman JL, Taylor RW, et al:

Effects of inhaled nitric oxide in patients with acute

respiratory distress syndrome: Results of a rando-

mized phase II trial. Inhaled Nitric Oxide in ARDS

Study Group. Crit Care Med 26:15-23, 1998.

78. Lundin S, Mang H, Smithies M, et al: Inhalation of

nitric oxide in acute lung injury: Results of a Euro-

pean multicentre study. The European Study Group

of Inhaled Nitric Oxide.Intensive Care Med 25:911-

919, 1999.

79. Gerlach H, Keh D, Semmerow A, et al: Dose-res-

ponse characteristics during long-term inhalation

of nitric oxide in patients with severe acute respira-

tory distress syndrome: A prospective, randomized,

controlled study. Am J Respir Crit Care Med

167:1008-1015, 2003.

80. Kaisers U, Busch T, Deja M, et al: Selective pulmo-

nary vasodilation in acute respiratory distress syn-

drome. Crit Care Med 31:S337-S342, 2003.

81. Katayama Y, Higenbottam TW, Diaz de Atauri MJ,

et al: Inhaled nitric oxide and arterial oxygen

tension in patients with chronic obstructive pulmo-

nary disease and severe pulmonary hypertension.

Thorax 52:120-124, 1997.

82. Barbera JA, Roger N, Roca J, et al: Worsening of

pulmonary gas exchange with nitric oxide inhala-

tion in chronic obstructive pulmonary disease.

Lancet 347:436-440, 1996.

83. Yoshida M,Taguchi O,Gabazza EC,et al: Combined

inhalation of nitric oxide and oxygen in chronic

obstructive pulmonary disease. Am J Respir Crit

Care Med 155:526-529, 1997.

84. Vonbank K, Ziesche R, Higenbottam TW, et al:

Controlled prospective randomised trial on the

effects on pulmonary haemodynamics of the

ambulatory long term use of nitric oxide and

oxygen in patients with severe COPD. Thorax

58:289-293, 2003.